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Trials like EMPAREG OUTCOME and REWIND underscore how newer medications reshape risk management, leading some experts to recommend earlier initiation of these agents in patients with elevated cardiovascular or renal risks

Now it seems oral small-molecule GLP-1s also dial back eating for pleasure by engaging a brain reward circuit. Given the effect of these drugs on eating for pleasure, future studies could explore whether small-molecule GLP-1s can also suppress cravings for other addictive substances

Employer-sponsored plans, Medicare, and Medicaid all handle this differently