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They are highly effective for many patients but carry risks including increased infection susceptibility, injection site reactions, and the development of anti-drug antibodies
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When those systems get stressed, natural peptide output declines, which is why adults often feel like their recovery switch is broken
Although a plethora of tumor cell mechanosensors have been identified, including focal adhesions, ion channels, actin cytoskeleton, nuclear proteins, and transcription factors, more research is needed to uncover how breast cancer cells convert biophysical signals into biochemical cues to mediate short- and long-term mechanoresponses ( Table 5 )
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