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This delayed gastric emptying effect may attenuate somewhat with continued use but remains clinically significant

As more people look for simple, ingredient-focused products, serums containing GHK-Cu are getting more attention for their role in cosmetic skin routines

The most-studied are Epitalon (telomeres), MOTS-c and Humanin (mitochondrial-derived peptides), SS-31 (mitochondrial protection), plus NAD+ and glutathione, which are non-peptide molecules studied alongside them for cellular energy and antioxidant balance

The effort needed to optimize these regimens can be experienced as aversive, promote frustration, and generate a desire to avoid such effort, aligning with a region of the brain called the anterior midcingulate cortex, as described by Lisa Feldman Barrett and colleagues