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B12, along with other B vitamins such as folate and vitamin B6, plays a crucial role in converting homocysteine into other substances, thereby helping to maintain its levels within a healthy range

Circ Res 90:966973 Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C et al (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele