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The downregulation of these proteins has been associated with OA progression [83]

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Therefore, more research, specifically randomised controlled trials would be needed to determine the efficacy and optimal dosage

Reduced glutathione is involved in the synthesis and repair of DNA, assists the recycling of vitamins C and E, blocks free radical damage, enhances the antioxidant activity of vitamin C, facilitates the transport of amino acids, and plays a critical role in detoxification