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3.1.2 Eligibility criteria This meta-analysis exclusively incorporated randomized controlled trials (RCTs) meeting the following inclusion criteria: (1) published clinical trials employing randomization (not restricted to double-blind designs)

doi: 10.1111/wrr.12939 92 ShiMZhuJWangRChenXMiLWalzTet al

As of October 2025, 13 Medicaid state plans cover at least one GLP1 receptor agonist

Both formulations showed significant improvement, which suggests similar topical efficacy for hydroquinone-based formulations (Ebrahimi and Naeini, 2014)