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As a regenerative medicine specialist deeply dedicated to evidence-based musculoskeletal treatments , including platelet-rich plasma (PRP) therapy , stem cell therapies , and advanced interventional musculoskeletal procedures , I feel it is essential to address these questions with scientific clarity

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Always perform the calculation yourself to confirm, as your specific protocol may require different doses

The applicant further opined that, although not explicitly stated, the paper presumably calculated the sample size based on the primary endpoint of stent removal, not to detect any clinical differences and, while Johnson et al