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The policy recognizes that research needs can change and institutions need assurance on product quality and suitability for their specific experimental applications

Importantly, animals were singly housed to eliminate the exchange and cross-contamination of intestinal microbiomes, a factor that potentially biases studies with group-housed animals by minimizing microbiome variations for co-housed animals within a cohort

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The time required for each rabbit to regain normal ambulation, without signs of lameness, was recorded