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Most people don't reach a full therapeutic dose until at least 817 weeks into the treatment, so meaningful results typically follow that timeline

Rheumatology 6(3):175178

Of four RCTs included in this meta-analysis that assessed the effect of L-carnitine supplementation in patients with NAFLD/ NASH, three studies reported that L-carnitine does not significantly affect lipid profile (Hong et al., 2014

Those with significant oxidative stress burdens or toxic exposures may experience continued improvements in overall wellbeing as cellular detoxification progresses