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A Step-by-Step Look at Its Effects on the Body When you take Mounjaro, tirzepatide gets to work in several ways simultaneously: Enhances Insulin Secretion: It prompts your pancreas to release insulin, but only when your blood sugar levels are rising, such as after a meal

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Of the total cohort, 117 participants (69.2%) had transitioned from DPP-4 inhibitors, and 5 participants (3.0%) were receiving concurrent insulin therapy

Adams JD Jr, Klaidman LK, Odunze IN, Shen HC, Miller CA (1991)