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Also, we recognize that presenting additional NNTs considering individual endpoints or groupings of endpoints (e.g., NNT 5-point MACE , NNT Major adverse kidney events ) would be useful to some readers or would allow a degree of comparison between the results of different trials

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The simultaneous activation of these three pathways is thought to increase research efficacy in weight and metabolic control studies without proportional increase in adverse gastrointestinal events seen with high concentration GLP-1 agonists alone

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