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Investigation of 2-deoxyadenosine-derived adducts specifically formed in rat liver and lung DNA by N -nitrosonornicotine metabolism

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And, while the actual rates of smoking-related cancers from 2006 to 2016 declined (annual percent change (APC) = 0.8, 95% CI = 1.0 to 0.5%), under the scenario of smoking elimination, the trend in cancer incidence at these sites was not declining (APC = 0.1, 95% CI = 0.4 to + 0.1%)