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these may include: persistent sadness or feelings of emptiness loss of interest or pleasure in activities once enjoyed irritability or restlessness anxiety or excessive worry difficulty concentrating or making decisions feelings of guilt, worthlessness, or hopelessness its important to note that these emotional symptoms may be more intense or persistent than the normal mood fluctuations one might experience when quitting smoking

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Moreover, because multiple macronutrients were examined across two time points, the study is susceptible to an increased risk of Type I error

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