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In some embodiments, administration of a formulation or composition or device described herein in combination with an otic intervention (e.g., an intratympanic injection, a stapedectomy, a medical device implant, or a cell-based transplant) delays or prevents collateral damage to auris structures, e.g., irritation, cell damage, cell death, osteoneogenesis, and/or further neuronal degeneration, caused by the external otic intervention (e.g., installation of an external device and/or cells in the ear)

The scanning protocol included a 1 mm 3 isotropic T 1 MPRAGE for voxel placement and segmentation

Novel analytical approach to a multi-sugar whole gut permeability assay

If you want the simplest possible dosing experience across the entire escalation schedule, aim for a 20mg/mL concentration regardless of vial size