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Using Summary data-based Mendelian Randomisation (SMR) analysis, we identified the targets of these drugs in the treatment of OP and further explored the associated biological processes, molecular functions, and signaling pathways to elucidate the underlying mechanisms of their therapeutic effects

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At the end of six months, significantly more participants who had received the 36 mg/mL nicotine ENDS, which has similar nicotine delivery to a cigarette, reported remaining abstinent from cigarettes compared to the other study groups