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The slowed gastric emptying may also reduce oral intake, as patients feel fuller longer and may struggle to consume adequate fluids

It also breaks down muscle for energy, especially when: Protein intake is insufficient Resistance training stimulus is absent Weight loss is too rapid Caloric deficit is too aggressive The Protein Paradox Here's where many GLP-1 users get stuck: you need more protein during weight loss, but GLP-1s make it harder to eat protein

The accumulation of such oxides affects various transcriptional activities and phosphorylation signals, thereby causing inflammation

Seattle, WA: University of Washington (2020) 27