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Injuries, joint pain, and slow recovery can disrupt daily life
Research shows that dose responsiveness varies significantly between individuals, with factors including metabolic adaptation, GLP-1 receptor polymorphisms, concurrent medication interactions, and adherence patterns all influencing clinical outcomes
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Table 1 Clinical characteristics of the 44 obese stone formers followed longitudinally The GLP-based therapies used during the weight loss intervention included semaglutide (86%), tirzepatide (48%), liraglutide (21%), and dulaglutide (14%), with patients switching between these agents on the basis of insurance coverage and/or medication availability
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