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Common side effects to be aware of when considering taking Pepto-Bismol products include: Blackening of the tongue Black stool Constipation Decreased urination Dry mouth Dizziness/light-headedness More serious side effects to be aware of include: Salicylate toxicity with symptoms such as headache, dizziness, confusion, ringing in the ears, trouble breathing, nausea, vomiting, stomach pain Allergic reaction Reyes Syndrome in children These are not all the possible side effects of Pepto-Bismol

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The model simulates the disease progression and projects the incidences of diabetes-related vascular complications and mortality based on the United Kingdom Prospective Diabetes Studies (UKPDS) 68 or 82 risk equations, combined with patient profiles and treatment effects of the therapies [13, 14]

While the absolute risk increase appears modest, it represents a clinically meaningful elevation requiring patient counseling and monitoring protocols