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A 2023 systematic review with meta-analysis showed that GLP-1 agonists significantly reduced body weight (11.7lb mean difference), body mass index (2.4kg/m2) and waist circumference (1.7 inches) in non-diabetic obese or overweight patients

1, 2, 3, 4 These drugs appear to be generally safe, however, a concern receiving increasing attention is the development of pancreatitis

Details of the registries and codes used for cancer diagnoses, drug exposure and covariates are provided in electronic supplementary material (ESM) Methods and ESM Tables 13

Lilly's revenue hit $17.60 billion, beating estimates by 9.5%, with Mounjaro generating $6.52 billion (up 109%) and Zepbound adding $3.57 billion (up 184%)