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When the antioxidant glutathione is administered intravenously, this causes an immediate boost in energy since the antioxidant is known to enhance mitochondrial energy production in cells

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Therefore, to test the assumption that GSH replenishment will rescue some of the AS cellular phenotypes, we supplemented the AS and the WT NPCs cell culture with GSH-EE, and first showed that GSH-EE increased the GSH levels in AS NPCs to normal WT NPCs levels, but did not significantly enhanced GSH levels in WT NPCs (Fig